Together 5,000 (T5k): Following a U.S. National Cohort of Vulnerable Men to Improve HIV Prevention and Care

This project addresses critical needs in HIV prevention research by using innovative technology to enroll a sample of 5,000 high-risk HIV-negative gay, bisexual, and other men who have sex with men ages 16 to 49—the population representing the highest percentage of new infections annually—and follow them prospectively for four years. The study design is specific to identifying individual-, network-, and contextual-level predictors and correlates of HIV seroconversion, identifying missed HIV prevention opportunities among those seroconverting during the course of the study, and using our findings to inform interventions to further reduce acquisition and transmission.