We explored the relationships between individuals’ behaviors, risk perceptions, and decisions to gather with other households during Thanksgiving in late November 2020 and the risk of subsequent SARS-CoV-2 test seeking and diagnosis. We found those who regularly engaged in higher COVID-19 risk activities and those who had a low-risk perception of COVID-19 were more likely to gather with other households for Thanksgiving. There was no association between gathering for Thanksgiving and subsequent COVID-19 infection or developing COVID-19 symptoms, both of which were self-reported measures. However, few participants reported receiving a COVID-19 test after Thanksgiving. 3.5% of those who gathered in our cohort tested positive after Thanksgiving. For more information, click here