University of Munich
University of Munich email@example.com
Dr. Geistlinger is trained in Bioinformatics. His research interests are in computational biology and biostatistics, focusing on the field of functional enrichment analysis of high-throughput genomic assay data.
Prior to his work at CUNY ISPH, Dr. Geistlinger completed a PhD on network-based analysis of gene expression data at the University of Munich, Germany, and a post-doctoral fellowship at the University of São Paulo, Brazil, where he analyzed the effects of structural genome variation on gene expression.
Dr. Geistlinger’s implementation science experience centers on designing and implementing methods for the analysis of large-scale genomic assay data to improve the understanding of molecular mechanisms underlying specific cancer types. This also includes assessment of the clinical relevance of molecular cancer subtypes, especially whether their incorporation in personalized healthcare could improve treatment and clinical outcome.
|• Human Microbiome Analysis for Public Health|
|• Validation and Clinical Relevance of Ovarian Cancer Molecular Subtypes|
|• Cancer genomics: integrative and scalable solutions in R/Bioconductor|
Geistlinger L, Da Silva VH, Cesar A, Tizioto PC, Waldron L, Zimmer R, De Almeida Regitano LC, Coutinho L. Widespread modulation of gene expression by copy number variation in skeletal muscle. Scientific reports. (2018) 8:1399. DOI:10.1038/s41598-018-19782-4.
Gegenfurtner FA, Jahn B, Wagner H, Ziegenhain C, Enard W, Geistlinger L, Rädler JO, Vollmar AM, Zahler S. Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing. J Cell Sci 2018 : jcs.212886 doi: 10.1242/jcs.212886. Published 3 May 2018.
Cesar ASM, Regitano LCA, Reecy JM, Poleti MD, Oliveira PSN, de Oliveira GB, Moreira GCM, Mudadu MA, Tizioto PC, Koltes JE, Fritz-Waters E, Kramer L, Garrick D, Beiki H, Geistlinger L, Mourão GB, Zerlotini A, Coutinho LL. Identification of putative regulatory regions and transcription factors associated with intramuscular fat content traits. BMC Genomics. 2018 Jun 27;19(1):499. doi: 10.1186/s12864-018-4871-y.
Chen GM, Kannan L, Geistlinger L, Kofia V, Safikhani Z, Gendoo DMA, Parmigiani G, Birrer MJ, Haibe-Kains B, Waldron L. Consensus on Molecular Subtypes of High-grade Serous Ovarian Carcinoma. Clin Cancer Res. 2018 Jul 3. pii: clincanres.0784.2018. doi: 10.1158/1078-0432.CCR-18-0784.
de Souza MM, Zerlotini A, Geistlinger L, Tizioto PC, Taylor JF, Rocha MIP, Diniz WJS, Coutinho LL, Regitano LCA. A comprehensive manually-curated compendium of bovine transcription factors. Sci Rep. 2018 Sep 13;8(1):13747. doi: 10.1038/s41598-018-32146-2.