Author: ISPH CUNY

Prevalence of and Factors Associated with the Use of HIV Serosorting and Other Biomedical Prevention Strategies Among Men Who Have Sex with Men in a US Nationwide Survey

Summary: PrEP and treatment-as-prevention (TasP) are biomedical strategies to reduce HIV transmission. Some men who have sex with men (MSM) are combining biomedical strategies with HIV serosorting-termed "biomed matching" when both partners are either on PrEP or TasP, or "biomed sorting" when one partner is using PrEP and the other TasP. The authors of the study expressed there is limited data on the extent of biomed matching/sorting in large geographically diverse samples. In 2016-2017, 5021 MSM from across the US were surveyed about their HIV status and HIV viral load/PrEP use, as well as...
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Is Cannabis Use Associated With Increased Risk of Cigarette Smoking Initiation, Persistence, and Relapse? Longitudinal Data From a Representative Sample of US Adults

Summary: This study prospectively investigated the relationship between cannabis use and cigarette smoking initiation, persistence, and relapse during a 3-year period among adults in the United States. Analyses included respondents who completed Waves 1 (2001-2002) and 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions and responded to questions about cannabis use and smoking status (n = 34,639). The study concluded that cannabis use was associated with increased initiation of, persistence of, and relapse to cigarette smoking. Additional attention to cannab...
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Screening and management of mental health and substance use disorders in HIV treatment settings in low- and middle-income countries within the global IeDEA consortium

Summary: Integration of services to screen and manage mental health and substance use disorders (MSDs) into HIV care settings has been identified as a promising strategy to improve mental health and HIV treatment outcomes among people living with HIV/AIDS (PLWHA) in low- and middle-income countries (LMICs). Data on the extent to which HIV treatment sites in LMICs screen and manage MSDs are limited. This study assesed practices for screening and treatment of MSDs at HIV clinics in LMICs participating in the International epidemiology Databases to Evaluate AIDS (IeDEA) consortium.  The study ...
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Data and Statistical Methods To Analyze the Human Microbiome

Summary: The Waldron lab for computational biostatistics bridges the areas of cancer genomics and microbiome studies for public health, developing methods to exploit publicly available data resources and to integrate -omics studies. Waldron Lab’s research discusses methods and resources for robust identification of differentially abundant microbes and predictive models of microbiome-linked health outcomes. It summarizes lessons from high-dimensional data analysis for cancer genomics and efforts by the lab to leverage and adapt the Bioconductor project for analysis and comprehension of high-...
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HIV treatment eligibility expansion and timely antiretroviral treatment initiation following enrollment in HIV care: A metaregression analysis of programmatic data from 22 countries

Summary: The effect of antiretroviral treatment (ART) eligibility expansions on patient outcomes, including rates of timely ART initiation among those enrolling in care, has not been assessed on a large scale. In addition, it is not known whether ART eligibility expansions may lead to "crowding out" of sicker patients.  This study investigated.  changes in timely ART initiation (within 6 months) at the original site of HIV care enrollment after ART eligibility expansions among 284,740 adult ART-naïve patients at 171 International Epidemiology Databases to Evaluate AIDS (IeDEA) network sites...
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The effect of albendazole treatment on non-seizure outcomes in patients with symptomatic neurocysticercosis

Summary: This study investigated the effect of albendazole on non-seizure symptoms experienced by patients with Neurocysticercosis (NC). Data was collected from a randomized controlled trial comparing albendazole plus prednisone with placebo plus prednisone for treatment of NC among 173 patients with active or transitional NC cysts and new-onset symptoms. Results showed 85% of patients reported at least one non-seizure symptom at baseline. Those treated with albendazole had significantly lower odds of memory loss and/or confusion during months 1–24 (odds ratio [OR] 0.42, p=0.037) and signif...
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Factors Influencing the Successful Implementation of HIV Linkage and Retention Interventions in Healthcare Agencies Across New York State

Summary: As part of the System Linkages and Access to Care Initiative, 12 HIV service delivery organizations in New York implemented one of the following three interventions to improve linkage to and retention in HIV care at their site: Peer Support, Appointment Procedures, and Anti-Retroviral Treatment and Access to Services. Process data from the interventions showed shortcomings in the percentage of eligible patients who went on to be enrolled, and the number of enrollees who ultimately received the components of the interventions. Factors identified in qualitative interviews that facili...
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Gaps along the HIV care continuum: findings among a population seeking sexual health care services in New York City

Summary: Linkage and re-linkage to HIV care for virally unsuppressed persons with new sexually transmitted infections is critical for ending the HIV epidemic. This study aimed to quantify HIV care continuum gaps, and viral suppression among HIV-positive in New York City sexual health clinics. The study authors assessed HIV care continuum outcomes before and after DOV (date of visit) for new-positives, prevalent-positives, and unknown-positives using registry laboratory data. The study concluded many HIV-positive persons, including those with uncontrolled HIV infection, attend SHCs and poten...
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Global analysis finds that expansion of national HIV treatment policies is associated with substantial increases in timely treatment initiation, especially among young persons with HIV

Global analysis finds that expansion of national HIV treatment policies is associated with substantial increases in timely treatment initiation, especially among young persons with HIV
For immediate release:  March 23, 2018 National adoption of the World Health Organization’s (WHO) HIV treatment guidelines has been followed by marked increases in timely initiation of antiretroviral treatment (ART), according to a recent analysis of HIV patient data from 22 countries where national ART guidelines and policies expanded HIV treatment eligibility, following WHO recommendations in 2009 and 2013. Increases in timely ART initiation were largest among young adults aged 16 to 24 years, and healthier patients with early stage disease—two groups that are known to have lower rates...
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